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Resuscitation Quick Ribbon (First 2 Minutes)

First-line Vasopressor:Norepinephrine 0.05–0.5 mcg/kg/min (Levophed); peripheral IV safe for up to 24–48h
Second-line Vasopressor:Vasopressin 0.03 units/min fixed dose (add when Norepinephrine reaches 0.25 mcg/kg/min)
Cardiogenic Inotrope:Dobutamine 2.5–20 mcg/kg/min OR Epinephrine 0.05–0.5 mcg/kg/min
Anaphylactic Shock:Epinephrine 0.3–0.5 mg IM (1:1,000) mid-outer thigh immediately; repeat q5–15min
Steroid Stress Dose:Hydrocortisone 100 mg IV (for refractory septic shock or suspected adrenal crisis)

Bottom-Line Clinical Pearl

Shock is cellular hypoxia and impaired tissue perfusion, NOT a blood pressure number. Tachycardia, altered mentation, mottled extremities, oliguria, and serum lactate > 2 mmol/L precede hypotension. Execute the RUSH protocol (Pump, Tank, Pipes) immediately. In septic/distributive shock, start Norepinephrine early rather than drowning the patient in excessive crystalloids. In cardiogenic shock, inotropes (Dobutamine, Milrinone) combined with Norepinephrine are required; aggressive fluid boluses cause flash pulmonary edema.

1. Hemodynamic Profiles of the 4 Shock States

Shock CategoryCardiac Output (CO)Preload (PCWP/CVP)Afterload (SVR)Central Venous O2 (ScvO2)Primary Etiologies
HypovolemicDecreasedDecreasedIncreasedDecreased (< 70%)Hemorrhage, dehydration, burns, third-spacing, DKA
CardiogenicDecreasedIncreasedIncreasedDecreased (< 60%)Acute MI, end-stage HF, acute MR/VSD, myocarditis, arrhythmias
ObstructiveDecreasedIncreased (or variable)IncreasedDecreasedTension pneumo, cardiac tamponade, massive PE, aortic dissection
DistributiveIncreased (early) / VariableDecreasedDecreased (Vasodilation)Increased (> 70%)Sepsis, anaphylaxis, neurogenic (spinal cord transection), adrenal crisis

2. The RUSH Protocol: Bedside Ultrasound for Undifferentiated Shock

ComponentUltrasound WindowLook ForKey Findings & Diagnoses
The PumpParasternal Long & Short, Apical 4-Chamber, SubxiphoidLV contractility, RV strain, Pericardial fluidPericardial effusion + RV collapse = Tamponade; Hyperdynamic LV = Sepsis/Hypovolemia; Dilated hypokinetic RV = Massive PE
The TankIVC, Lung Apices, Morison's Pouch, Splenorenal, PelvisIntravascular fullness, Pleural sliding, Free fluidCollapsing IVC (< 1.5 cm) = Hypovolemia; Plethoric IVC (> 2.1 cm) = Cardiogenic/Obstructive; Absent lung sliding = Pneumothorax; Free peritoneal fluid = Hemoperitoneum / Ruptured ectopic
The PipesAbdominal Aorta, Femoral & Popliteal VeinsAortic diameter, DVT compressionAbdominal aorta > 3 cm = AAA rupture; Non-compressible deep vein = DVT leading to massive PE
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