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Resuscitation Quick Ribbon (First 2 Minutes)

PALS Epinephrine:0.01 mg/kg IV/IO (0.1 mL/kg of 1:10,000 solution) q3–5min
Fluid Bolus (Shock):10–20 mL/kg balanced crystalloid over 10–20 min; re-evaluate liver edge and lung crackles
Dextrose (Hypoglycemia):D10W 5 mL/kg IV bolus (or D25W 2 mL/kg for children > 1 year)
Croup (Moderate/Severe):Dexamethasone 0.6 mg/kg PO/IM (max 16 mg) + Nebulized Racemic Epinephrine 0.5 mL in 3 mL saline
Neonatal Empiric Abx:Ampicillin 50 mg/kg IV q8h + Gentamicin 2.5 mg/kg IV q12h (or Cefotaxime 50 mg/kg)

Bottom-Line Clinical Pearl

Children are not small adults: bradycardia is the primary cardiac response to hypoxia and shock. The febrile infant under 28 days old requires a full sepsis workup (blood cultures, catheterized UA, and lumbar puncture) and empiric admission on IV ampicillin and ceftazidime/gentamicin. In infants 29–60 days, validated criteria (Rochester/Philadelphia) guide selective workup. In pediatric cardiac arrest, prioritize ventilation (1 breath q2–3s) and deliver Epinephrine 0.01 mg/kg (0.1 mL/kg of 1:10,000).

1. Febrile Infant Algorithm by Age Group

Age WindowRisk LevelMandatory Diagnostic WorkupEmpiric Management
0–28 days (Neonate)Extreme high risk (Listeria, GBS, E. coli, HSV)CBC, blood cultures x2, catheter UA/culture, Lumbar Puncture, chest X-rayAdmit to PICU/Peds; Ampicillin 50 mg/kg + Ceftazidime 50 mg/kg (add Acyclovir if vesicles/seizures)
29–60 daysIntermediate riskCatheter UA, blood cultures, inflammatory markers (procalcitonin/CRP), LP if high riskIf low-risk criteria met: Ceftriaxone 50 mg/kg IM and 24h follow-up; if high-risk: LP + admit
61–90 daysLow risk if immunizedCatheter UA and urine culture; clinical assessmentOutpatient management if well-appearing and urine negative
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